Guardian of genome?

Guardian of genome is -------------
a) p53
b) bcl2
c) bcl1
d) BRCA


Ans: A


P53 also known as protein 53 or tumor protein 53 is tumor suppressor protein that in human is encoded by the TP 53 gene. In multicellular organisms it regulates the cell cycle and thus function as a tumor suppressor.It has been described as a GURDIAN OF GENOME because its role in conserving stability by preventing genome mutation.